When people think of testosterone, they often associate it with muscle growth, energy, and libido. But what if your hormonal health could also be affecting your gut? This Irritable Bowel Syndrome Awareness Month, it's time to talk about the unexpected connection between IBS and low testosterone — a link that could be playing a bigger role in digestive issues than many men realize.

The Overlooked Connection Between Testosterone and Gut Health
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that affects an estimated 10-15% of adults in the United States, causing symptoms like abdominal pain, bloating, diarrhea, constipation, and fatigue. While IBS is often more commonly reported in women, men are frequently underdiagnosed, and research suggests that low testosterone levels may contribute to IBS symptoms.
A 2022 study published in The Journal of Clinical Investigation found that men with IBS had significantly lower free testosterone levels than men without IBS.
Researchers also observed that testosterone played a role in regulating gut motility, meaning that low testosterone levels could contribute to the slowed digestion and discomfort that many men with IBS experience.
This emerging research suggests that hormonal health isn’t just about reproductive function — it’s deeply connected to overall well-being, including digestive health.
How Low Testosterone Affects Digestion

Testosterone influences multiple functions in the body, from metabolism to brain health. But can irritable bowel syndrome cause weight gain? While IBS itself doesn’t always lead to weight gain, it can indirectly contribute to it due to hormonal imbalances, stress-related overeating, and slowed digestion.
According to research, here’s how low testosterone might be impacting your gut health:
- Slower Gut Motility: Testosterone plays a role in regulating colonic motility, the process that moves food through the intestines. When testosterone levels drop, the intestines may not function as efficiently, leading to constipation and bloating.
- Increased Gut Sensitivity: Low testosterone levels may heighten pain perception, making men more likely to experience IBS-related cramping and discomfort.
- Imbalance in the Gut Microbiome: Research suggests that hormonal changes can alter the gut microbiome, which may exacerbate IBS symptoms and contribute to intestinal inflammation.
- Fatigue and Energy Disruptions: Irritable bowel syndrome and fatigue often go hand in hand. Because testosterone supports energy levels and metabolism, low levels may contribute to chronic tiredness and sluggish digestion.
The Hidden Epidemic: Why Men Should Be Screened for Hormonal Imbalances
Despite testosterone's importance, many men aren’t aware that their gut symptoms could be tied to hormone levels. In fact, IBS is often dismissed as a stress-related or diet-based disorder, leading men to ignore potential underlying causes like low testosterone.

If you're experiencing chronic digestive issues, unexplained fatigue, or weight fluctuations, it's essential to ask your healthcare provider to check your hormone levels. A simple blood test can determine whether low testosterone may be a contributing factor to your IBS symptoms.
Signs of Low Testosterone That Overlap with IBS
- Unexplained fatigue or low energy levels
- Unintentional weight gain or muscle loss
- Brain fog or difficulty concentrating
- Low libido or sexual dysfunction
- Mood changes, including increased anxiety or irritability
Because IBS and hormonal imbalances share many overlapping symptoms, it’s important to take a holistic approach to managing both.
IBS Management: Can Testosterone Replacement Therapy Help?
For men who have both low testosterone and type 2 diabetes, there has been significant research showing that testosterone replacement therapy (TRT) may improve metabolic and overall health outcomes. But can TRT also help with IBS symptoms?
While more research is needed, the findings from The Journal of Clinical Investigation suggest that restoring testosterone levels in testosterone-deficient men could improve gut motility and reduce IBS symptoms.
However, TRT isn’t the only solution. Managing testosterone and gut health requires a multi-faceted approach:
Steps to Balance Hormones and Improve Gut Health
- Get Your Hormones Checked: If you experience persistent IBS symptoms, a testosterone blood test may help identify if low T is a contributing factor.
- Optimize Your Diet: Eating fiber-rich foods, lean proteins, and healthy fats can support both testosterone production and digestive health.
- Reduce Stress: Chronic stress can contribute to both IBS flare-ups and low testosterone. Incorporating stress management techniques like deep breathing, meditation, and exercise can help.
- Strength Training and Exercise: Regular exercise can boost testosterone levels and help regulate digestion by improving gut motility.
- Improve Sleep Quality: Poor sleep negatively affects both testosterone production and gut health, so aim for 7–9 hours of quality sleep per night.
Why Men’s Hormonal Health Needs More Attention
IBS Awareness Month isn’t just about recognizing digestive symptoms — it’s about understanding how gut health is linked to overall well-being, including testosterone levels.
Men often overlook signs of hormonal imbalance because they assume symptoms like fatigue, weight changes, or digestive discomfort are just part of aging. However, new research is revealing that hormones play a crucial role in gut health, and balancing testosterone levels could be key to reducing IBS symptoms.
If you’ve been struggling with persistent IBS symptoms and fatigue, it may be time to take a closer look at your hormonal health. This IBS Awareness Month, make gut health a priority — and don’t overlook testosterone’s role in digestive wellness.
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